Examples of autoimmune diseases that have responded to stem cell therapy either in animals or humans include (but not limited to) Diabetes Mellitus Type 1, Rheumatoid Arthritis (RA), Multiple Sclerosis (MS), and Systemic Lupus Erythematosus (SLE), Parkinson’s Disease, Ulcerative Colitis, Crohn’s Disease as well as Scleraderma.
Besides healing damaged tissues, stem cells have the unique ability to influence the immune system, shutting off pathological responses of the autoimmunity, while preserving its ability to fight off disease. Stem cells and specifically, mesenchymal stem cells target and are attracted to inflamed tissue and start producing anti-inflammatory agents. Mesenchymal stem cells have the potential to induce the production of T regulatory cells, a type of immune cell whose function is to protect the body against immunological self-attack.
According to WHO nearly 600 million people worldwide have arthritis. It is a leading cause of work disability. The good news is that stem cells have been shown to be very effective in degenerative arthritis (osteoarthritis) and sports injuries.
Arthritis involves the breakdown of articular cartilage as the result of disease and/or damage similar to cartilage damage of sports injuries and due to normal wear and tear. Articular cartilage is found particularly in the joints of the body such as hips, knees, hands, shoulders, spine, and pelvis – only to mention few. When the smooth gliding surfaces of the joint are no longer intact, arthritis occurs causing inflammation, pain, swelling and stiffness.
Conventional methods used to treat arthritis and sports injuries (involving damaged joints, tendons, and/or ligaments) include anti-inflammatories, physical therapy, analgesics, and common surgery. Alternative methods are used as well and typically include glucosamine, chondroitin, hyaluronic acid, methylsulfonylmethane (MSM), omega-3 fatty acids, and proven herbs such as turmeric.
Stem cell therapy is increasingly being used for arthritis and sports injuries and is very effective in not only alleviating pain but regenerating the damaged cartilage or tendon. Many professional athletes are now turning to stem cell therapy to treat their injuries and see faster results and recovery.
Depending on the patient and their needs, we use a combination of stem cell therapy combined with the growth factors in PL, along with hyaluronic acid (if indicated) with various ingredients/nutrients that make up our proprietary stem cell cocktails to treat their ailments.
Rheumatoid Arthritis (RA), is a chronic, system-wide inflammatory disorder that may affect many tissues and organs. RA is considered a systemic autoimmune disease where essentially, antibodies in the body attack the patient’s own healthy cells. Although the cause of RA is unknown, autoimmunity plays a pivotal role in both its chronic status and progression. RA primarily attacks the joints. The disease process often leads to the decay of articular cartilage and ankylosis (abnormal immobility and fusion of bones) of the joints. Rheumatoid Arthritis can also produce diffuse inflammation in the lungs, pericardium, pleura, and sclera, and also nodular lesions, most common in subcutaneous tissue.
Diabetes is a condition where the body has problems controlling blood sugar levels. There are two main types of diabetes Mellitus.
In Diabetes Type I, the body mounts and in immune response (autoimmune) to its own insulin-producing beta cells in the pancreas and damages said cells. In Diabetes Type II, there is either an insufficient production of insulin or the insulin that is produced is not responded to well by the peripheral cells (insulin-resistance). Diabetes Type II is manageable with the proper diet and exercise in most cases whereas Diabetes Type I requires that patients test their blood sugar levels regularly and administer insulin as necessary through an injection or a pump.
Mesenchymal stem cells derived from the Bone marrow as well as from endometrial tissue are the cells that we use at the Stem Cell Healing Institute. We find this combination successful for Autoimmune Disease and inflammation. They are multipotent cells that can generate multiple cell lineages.
We specifically inject directly into the Pancreatic Circulation as well as the Inguinal Lymph Node. This targets and modulates the antibodies that attack the beta cells of the Pancreas. The cells are injected into the patient where they will allocate to the pancreas and either support the repair of beta cells in the patient or ideally differentiate into beta cells themselves which would then regulate the levels of insulin in the patient’s body.
Depending and the type of Diabetes, the treatment, amount of cells and number of times the procedure is repeated and the results will vary.
Multiple Sclerosis is a disease that affects the central nervous system. It is a long-term autoimmune disease. It happens when the immune system attacks the myelin sheath that covers nerve fibers, causing nerves to become inflamed and damaged. This can cause a wide range of symptoms, such as tiredness, muscle weakness, trouble with coordination, balance and mobility, eye problems, problems with the bladder and bowel, memory loss, and changes in mood. MS can manifest differently from person to person. Some people remain functional on a daily basis while others can be severely debilitated. The symptoms of MS can potentially progress and worsen over time unless a patient is in remission.
Stem cell therapy has shown promise in treating MS. This treatment includes taking stem cells from the patient’s bone marrow or blood and then modulating the immune cells that are attacking the myelin sheath. Clinical studies have shown that stem cells can help slow or even stop MS from getting worse (in remission). In one study, 78% of people who had stem cell therapy did not have any disease activity after five years, while only 2% of people who had traditional care did not.
This study found that stem cells worked better than standard treatment at reducing relapses and making people with aggressive MS less disabled: ‘Stem Cell Transplant Stops Multiple Sclerosis in its Tracks.’ Dr. Michael Sy, MD. This is the headline from WAFB who spoke with neurologist, Dr. Michael Sy, MD at the University of California, Irvine. Drugs to treat Multiple Sclerosis can cost up to $100,000 per year but Dr. Michael Sy continues: ‘Because the stem cell transplant therapy allows patients to get off all their medications, in the long run, researchers believe this will not only be lifesaving, but also cost effective.’
Dr. Sy explains, “Bone marrow transplant offers the opportunity to just completely reset the immune system.”
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