Platelet Lysate Therapy
Platelet Lysate Growth Factor Therapy
The Platelet Lysate Growth Factor Therapy Program
Platelet Lysate Therapy Growth Factor is a great way to use your own body’s resources to repair damaged tissues, joints, tendons, ligaments, and skin. Platelet Lysate Therapy allows for only concentrated growth factors to be injected into damaged tissues as opposed to other inflammatory cells and other components of blood.
Here is how the process works:
- The doctor will extract a small amount of blood from your arm
- The vial of blood is then placed in a centrifuge and spun at a very fast rate allowing for the blood and to separate from the platelets from the other components of the blood
- The platelets will then be frozen at specific temperatures and times to isolate the inherent growth factors
Growth Factor known effects:
- Epidermal Growth Factor (EGF) – Stimulates fibroblasts to secrete collagenase to degrade the matrix during the remodeling phase. Stimulates keratinocyte and fibroblast proliferation.
- Transforming Growth Factor- Promotes angiogenesis, up-regulates collagen production and inhibits degradation, promotes chemo attraction of inflammatory cells.
- Vascular Endothelial Growth Factor (VEGF) – Endothelial cells promote angiogenesis during tissue hypoxia.
- Fibroblast Growth Factor (FGF) – Promotes angiogenesis, granulation, and epithelialization via endothelial cell, fibroblast, and keratinocyte migration, respectively.
- Platelet-Derived Growth Factor (PDGF) – Attracts macrophages and fibroblasts to zone of injury. Promotes collagen and proteoglycan synthesis.
- Interleukins, Macrophages, keratinocytes, endothelial cells, lymphocytes, fibroblasts, osteoblasts, basophils, mast cells – Activates fibroblast differentiation. Induces collagen and proteoglycan synthesis.
- Colony Stimulating Factors – Stimulates granulocyte and macrophage proliferation.
- Keratinocyte Growth Factor – Fibroblasts stimulate keratinocyte migration, differentiation, and proliferation.